A carrier device and methods of use are described. The device and methods are directed toward implanting in biological tissue and optionally for propelling in a biological tissue and for releasing a medical payload in a biological tissue according to remote trigger. The carrier device includes at least one element sensitive to the external stimuli. When external stimuli are sent through the tissue, the responsive element provides release of the functional material. In some embodiments, payload release can be started, stopped, and restarted at a later time or place. Individual carrier devices can be selectively triggered by implementing different elements in the devices, each element is sensitive to different stimuli. In addition to payload release, devices of this invention are equipped with a propelling element, the propelling element is responsive to external stimuli that enables propulsion and navigation of the device.
