MAO JEREMY J.;CHEN MO;THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK
发明人:
MAO JEREMY J.,CHEN MO
申请号：
US201113877262
公开号：
US2014093481(A1)
申请日:
2011.10.03
申请国别(地区):
美国
年份:
2014
代理人:
摘要：
One aspect provides a method of forming a mineralized material by co-culturing a epithelial cell, such as ameloblasts, and mesenchymal cells, such as osteoblasts or odontoblasts, in a mineral-stimulating medium. Another aspect provides matrix seeded with epithelial cells and mesenchymal cells and infused with a mineral-stimulating medium capable of forming a mineralized material in the matrix. Methods of manufacturing such compositions and methods of treating mineralization-related conditions are also provided.
