THREE -DIMENSIONAL WATER CONGREGATES OF PHOSPHOLIPIDES DERIVED IN ALCOLIC MIXES BASED OR WITHOUT WATER CONTENT, THEIR PREPARATION AND USE IN TOPIC APPLICATION FORMULATIONS
MANCA, Maria Letizia,MANCONI, Maria,FADDA, Anna Maria,MANCA MARIA LETIZIA,MANCONI MARIA,FADDA ANNA MARIA
申请号:
IT201700034725
公开号:
IT201700034725A1
申请日:
2017.03.29
申请国别(地区):
IT
年份:
2018
代理人:
摘要:
The present invention relates to three-dimensionally aggregated vesicles formed by phospholipid molecules and at least one pharmacologically and/or cosmetically active principle, preferably water-insoluble, but also water-soluble, which are dispersed in a carrier substantially consisting of mixtures having a different composition of alcohols, polyalcohols and/or polyoxyethylenes, in the presence or absence of water (from 0 to 25% v/v of the dispersing carrier; preferably 0 to <;25% v/v). The invention also relates to the preparation of said three-dimensionally aggregated phospholipid-based vesicles and to the use thereof in topical compositions for carrying said pharmaceutical and/or cosmetic active substances.