DEMATTOS, RONALD B.,MAY, PATRICK CORNELIOUS,SIMS, JOHN R.
申请号：
CA3014669
公开号：
CA3014669A1
申请日:
2017.03.10
申请国别(地区):
CA
年份:
2017
代理人:
摘要：
The present invention provides a method of treating a cognitive or neurodegenerative disease, comprising administering to a patient in need of such treatment an effective amount of (1r,1R,4R)-4-methoxy-5"-methyl-6-[5-(prop-1-yn-1-yl)pyridin-3-yl]-3H-dispiro[cyclohexane-1,2-indene-1,2"-imidazol]-4"-amine, or a pharmaceutically acceptable salt thereof (including the camsylate salt thereof) in combination with an effective amount of an anti-N3pGlu Abeta antibody.
