Demattos, Ronald B.,May, Patrick Cornelious,Sims, John R.
申请号:
AU2017234643
公开号:
AU2017234643A1
申请日:
2017.03.10
申请国别(地区):
AU
年份:
2018
代理人:
摘要:
The present invention provides a method of treating a cognitive or neurodegenerative disease, comprising administering to a patient in need of such treatment an effective amount of (1r,1'R,4R)-4-methoxy-5"-methyl-6'-[5-(prop-1-yn-1-yl)pyridin-3-yl]-3'H-dispiro[cyclohexane-1,2'-indene-1',2"-imidazol]-4"-amine, or a pharmaceutically acceptable salt thereof (including the camsylate salt thereof); in combination with an effective amount of an anti-N3pGlu Abeta antibody.