Robert Lewis Steele;Russell Van de Casteele;Anthony Fedele Musso;David D. Mundschenk
发明人:
Robert Lewis Steele,Anthony Fedele Musso,David D. Mundschenk,Russell Van de Casteele
申请号：
US14201740
公开号：
US20140256761A1
申请日:
2014.03.07
申请国别(地区):
US
年份:
2014
代理人:
摘要：
The present invention describes a method of treating individuals suffering from microbial infections, including a parasitic disease such as malaria, by using an improved Artemisinin Combination Therapy (ACT), known as ActRx Tri-ACT Plus. The improved ACT therapy includes administering a combination of four drugs. In one embodiment of the present invention, the method includes administering to an individual a first composition comprising a therapeutically effective amount of an artemether spray sublingually. The individual is then administered a second composition, a therapeutically effective amount of artesunate. A third composition, an effective amount of berberine, or its pharmaceutically acceptable derivatives or salts is administered to the individual. A fourth composition, an effective amount of primaquine, or its pharmaceutically acceptable derivatives or salts is administered to the individual.
