PROBLEM TO BE SOLVED: To provide an IgG-type antibody adsorbent that carries a peptide capable of interacting with IgG type antibodies with high affinity in a process for adsorbing and removing autoantibodies and immune complexes contained in the plasma by an adsorbent to prevent the progress of autoimmune disease and alleviate the symptoms of the disease.SOLUTION: According to the present invention, there is provided an IgG-type antibody adsorbent 9 comprising a water-insoluble carrier and a peptide carried on the water-insoluble carrier, the peptide having a specific amino acid sequence. There is also provided an IgG-type antibody adsorber 1 comprising: a container having an inlet port 5 for allowing a liquid to flow therein and an outlet port 7 for allowing the liquid to flow out thereof and the IgG-type antibody adsorbent filled in the container. There is further provided a body fluid purification device 1 in which a liquid flowing into IgG-type antibody adsorber 1 is a body fluid selected from the blood, plasma, and serum.SELECTED DRAWING: Figure 1COPYRIGHT: (C)2017,JPO&INPIT【課題】自己免疫疾患の進行を防止、疾患の症状を軽減させるため、血漿中に含まれる自己抗体及び免疫複合体を吸着剤によって吸着・除去する方法にあって、IgG型抗体と高い親和性で相互作用するペプチドを担持したIgG型抗体吸着材の提供。【解決手段】水不溶性担体と、前記水不溶性担体に担持されたペプチドとを含み、前記ペプチドが特定のアミノ酸配列を有する免疫グロブリンG(IgG)型抗体吸着材9、及び液体を流入させる入口ポート5と、前記液体を流出させる出口ポート7と、を有する容器と、前記容器に充填されたIgG型抗体吸着材とを備えるIgG型抗体吸着器1、並びにIgG型抗体吸着器1に流入する液体が血液、血漿及び血清から選択される体液である、体液浄化デバイス1。【選択図】図1
