Rey Diego Ariel,de Forest Nikol,Cox Heather,Shukla Soni
申请号：
US201615180790
公开号：
US9771622(B2)
申请日:
2016.06.13
申请国别(地区):
美国
年份:
2017
代理人:
Chang David J.
摘要：
Methods and systems are provided for packaging reporter nucleic acid molecules into non-replicative transduction particles for use as reporter molecules. The non-replicative transduction particles can be constructed from viruses and use viral transduction and replication systems. The reporter nucleic acid molecules include a reporter gene, such as a reporter molecule or selectable marker, for detecting target genes or cells. Methods and systems are provided for detection of cells and target nucleic acid molecules using the non-replicative transduction particles as reporter molecules.
