The present invention relates to pyrrolidin-2-one, pyrrolidin-2,5-dione, pyrrolidine and thiosuccinimide compounds, and methods of preparation of these compounds. The present invention also relates to pharmaceutical compositions comprising pyrrolidin-2-one, pyrrolidin-2,5-dione, pyrrolidine and thiosuccinimide compounds. The present invention provides methods of treating a cell proliferative disorder, such as a cancer, by administering to a subject in need thereof a therapeutically effective amount of a compound of pyrrolidin-2-one, pyrrolidin-2,5-dione, pyrrolidine and thiosuccinimide compound of the present invention.本發明係關於吡咯啶-2-酮、吡咯啶-2,5-二酮、吡咯啶及硫代琥珀醯亞胺化合物及此等化合物之製備方法。本發明亦係關於包含吡咯啶-2-酮、吡咯啶-2,5-二酮、吡咯啶及硫代琥珀醯亞胺化合物之藥學組成物。本發明提供經由對有需要之個體投予治療有效量之本發明化合物或吡咯啶-2-酮、吡咯啶-2,5-二酮、吡咯啶及硫代琥珀醯亞胺化合物用以治療細胞增殖病症諸如癌症之方法。
