Jianqiang Wang,Syed M. Ali,Eugene Kelleher,Yanbin Liu,Jason Hill,Mark A. Ashwell
申请号：
US12664550
公开号：
US08304425B2
申请日:
2008.06.19
申请国别(地区):
US
年份:
2012
代理人:
摘要：
The present invention relates to pyrrolidin-2-one, pyrrolidin-2,5-dione, pyrrolidine and thiosucciniroide compounds of formulae (I)-(IV), and methods of preparation of these compounds. The present invention also relates to pharmaceutical compositions comprising pyrrolidin-2-one, pyrrolidin-2,5-dione, pyrrolidine and thiosuccinimide compounds. The present invention provides methods of treating a cell proliferative disorder, such as a cancer, by administering to a subject in need thereof a therapeutically effective amount of a compound of pyrrolidin-2-one, pyrrolidin-2,5-dione, pyrrolidine and thiosuccinimide compound of the present invention.
