KIM, DONG YEON,金东渊,金東淵,CHO, DAE JIN,赵大祯,趙大禎,LEE, GONG YEAL,李宫烈,李宮烈,KIM, HONG YOUB,金洪烨,金洪燁,WOO, SEOK HUN,禹锡勳,禹錫勳,LEE, HAE UN,李海盎,KIM, SUNG MOO,金嵩武,AHN, CHOONG AM,安钟恩,安鐘恩,YOON, SEUNG BIN,允承彬
申请号:
TW101111335
公开号:
TWI434836B
申请日:
2012.03.30
申请国别(地区):
TW
年份:
2014
代理人:
摘要:
Disclosed are a phenyl-isoxazol derivative compound represented by Formula 1 below, which is useful as a treatment material for virus infection, especially, infection of an influenza virus, or its pharmaceutically acceptable derivative, a preparation method thereof,, and an illness treatment pharmaceutical composition including the compound as an active ingredient:wherein in Formula above R1, R2, R3, R4and R8are the same as defined in the specification.揭露下面分子式1所表示的苯基-異噁唑衍生物化合物,或其藥理上可接受之衍生物,其可用來治療病毒之感染,尤其是流感病毒之感染,並揭露其製備方法,也揭露包含做為活性成份之該化合物的疾病治療藥物組成:其中在上面分子式中,R1,R2,R3,R4及R8相同於說明書中所界定者。