作為ＰＧＤＳ抑制劑之苯基二唑衍生物农业专利-农业学术服务平台

发明人:: VANDEUSEN, CHRISTOPHER L.,范德森　克里斯托弗,WEIBERTH, FRANZ J.,魏伯斯　弗朗茨,GILL, HARPAL S.,吉尔　哈帕尔,吉爾　哈帕爾,LEE, GEORGE,李　乔治,李　喬治,HILLEGASS, ANDREA,希尔盖斯　安德烈,希爾蓋斯　安德烈,范德森克里斯托弗,魏伯斯弗朗茨,吉尔哈帕尔,吉爾哈帕爾,李乔治,李喬治,希尔盖斯安德烈,希爾蓋斯安德烈

摘要：: This invention is directed to a compound of formula (I):wherein R1, R2 and R3 are as defined herein, a pharmaceutical composition comprising the compound, intermediates and processes for making said compounds, and the use of the compound to treat allergic and/or inflammatory disorders, particularly disorders such as allergic rhinitis, asthma, chronic obstructive pulmonary disease (COPD) and age-related macular degeneration (AMD).本發明係針對一種式(I)化合物：其中R1、R2和R3如本文所定義，一種含有此化合物的醫藥組成物、製備上述化合物的中間體和方法，以及使用此化合物治療過敏性和/或發炎性疾病之用途，尤其是例如過敏性鼻炎、哮喘、慢性阻塞性肺病(COPD)以及年齡相關黃斑變性(AMD)之疾病。