POLYPEPTIDES FGF-21 MODIFIÉES ET LEURS UTILISATIONS

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专利权人:

Bristol-Myers Squibb Company

发明人:

申请号：

EP18177893.7

公开号：

EP3412302A1

申请日:

2015.10.23

申请国别(地区):

EP

年份:

2018

代理人:

摘要：

Modified FGF-21 polypeptides and uses thereof are provided, for example, for the treatment of diseases associated with fibrosis. Modified FGF-21 polypeptides are disclosed that contain an internal deletion and optionally replacement peptide, optionally modified with at least one non-naturally-encoded amino acid, and/or optionally fused to a fusion partner.

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