Jonathan Mark Bentley,Daniel Christopher Brookings,Julien Alistair Brown,Thomas Paul Cain,Laura Jane Gleave,Alexander Heifetz,Victoria Elizabeth Jackson,Craig Johnstone,Deborah Leigh,James Madden,John
申请号:
US14414299
公开号:
US20150191482A1
申请日:
2013.07.05
申请国别(地区):
US
年份:
2015
代理人:
摘要:
A series of imidazo[1,2-α]pyrazine derivatives, being potent modulators of human TNFα activity, are accordingly of benefit in the treatment and/or prevention of various human ailments, including autoimmune and inflammatory disorders; neurological and neurodegenerative disorders; pain and nociceptive disorders; cardiovascular disorders; metabolic disorders; ocular disorder; and oncological disorders.