Daniel Christopher Brookings,Teresa De Haro Garcia,Yann Foricher,Helen Tracey Horsley,Martin Clive Hutchings,James Andrew Johnson,Malcolm Maccoss,Mengyang Xuan,Zhaoning Zhu
申请号:
US16497217
公开号:
US20200046723A1
申请日:
2018.04.24
申请国别(地区):
US
年份:
2020
代理人:
摘要:
A compound of formula (I) as defined herein, or a pharmaceutically acceptable salt thereof, being potent modulators of human TNFα activity, are accordingly of benefit in the treatment and/or prevention of various human ailments, including autoimmune and inflammatory disorders; neurological and neurodegenerative disorders; pain and nociceptive disorders; cardiovascular disorders; metabolic disorders; ocular disorders; and oncological disorders.