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Fused tricyclic imidazole derivatives as modulators of TNF activity
专利权人:
UCB BIOPHARMA SPRL
发明人:
Rikki Peter Alexander,Gareth Neil Brace,Julien Alistair Brown,Mark Daniel Calmiano,Prafulkumar Tulshibhai Chovatia,Michael Deligny,Ellen Olivia Gallimore,Jag Paul Heer,Victoria Elizabeth Jackson,Boris
申请号:
US15101767
公开号:
US10087179B2
申请日:
2014.12.08
申请国别(地区):
US
年份:
2018
代理人:
摘要:
A series of fused tricyclic imidazole derivatives, in particular dihydro-1H-cyclopenta[4,5]imidazo[1,2-a]pyridine derivatives, and analogues thereof, being potent modulators of human TNFα activity, are accordingly of benefit in the treatment and/or prevention of various human ailments, including autoimmune and inflammatory disorders; neurological and neurodegenerative disorders; pain and nociceptive disorders; cardiovascular disorders; metabolic disorders; ocular disorders; and oncological disorders.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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