ALEXANDER HEIFETZ,CRAIG JOHNSTONE,DANIEL CHRISTOPHER BROOKINGS,DEBORAH LEIGH,JAMES MADDEN,JOHN ROBERT PORTER,JONATHAN MARK BENTLEY,JULIEN ALISTAIR BROWN,LAURA JANE GLEAVE,MATTHEW DUNCAN SELBY,THOMAS P
申请号：
BR112015000790
公开号：
BR112015000790A2
申请日:
2013.07.05
申请国别(地区):
BR
年份:
2017
代理人:
摘要：
A series of imidazo[1,2-&alpha；]pyrazine derivatives, being potent modulators of human TNF&alpha； activity, are accordingly of benefit in the treatment and/or prevention of various human ailments, including autoimmune and inflammatory disorders； neurological and neurodegenerative disorders； pain and nociceptive disorders； cardiovascular disorders； metabolic disorders； ocular disorder； and oncological disorders.
