STEFATER, James, Anthony III,STRYJEWSKI, Tomasz, Pawel
申请号：
EP17828468
公开号：
EP3484534A4
申请日:
2017.07.13
申请国别(地区):
EP
年份:
2020
代理人:
摘要：
The invention provides methods and polymer compositions for treating retinal detachment and other ocular disorders, where the methods employ polymer compositions that can form a hydrogel in the eye of a subject. The hydrogel is formed by reaction of (i) a nucleo-functional polymer that is a biocompatible polymer containing a plurality of thio-functional groups —R1—SH wherein R1 is an ester-containing linker, such as a thiolated poly(vinyl alcohol) polymer and (ii) an electro-functional polymer that is a biocompatible polymer containing at least one thiol-reactive group, such as a poly(ethylene glycol) polymer containing alpha-beta unsaturated ester groups.
