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CORE-SHELL COMPOSITE MATERIAL
专利权人:
AGENCY FOR SCIENCE; TECHNOLOGY AND RESEARCH
发明人:
SINGH, Harjinder,HAIGH, Brendan,ROY, Nicole,KIRYUKHIN, Maxim,ANTIPINA, Maria,NOVOSELOVA, Marina,SUKHORUKOV, Gleb
申请号:
SG11201803496R
公开号:
SG11201803496RA
申请日:
2016.10.26
申请国别(地区):
SG
年份:
2018
代理人:
摘要:
Disclosed herein is a core-shell composite material comprising: a core optionally comprising an active ingredient compound a shell structure comprising at least two alternating layers the alternating layers being a protein layer and a polyphenol layer and optionally a polyelectrolyte layer interfacing said core and said shell structure, said polyelectrolyte layer being disposed adjacent to said protein layer or said polyphenol layer, wherein said shell structure is selected to be resistant to degradation under gastric conditions but is degradable by one or more intestinal enzymes. In a preferred embodiment the protein is bovine serum albumin (BSA) or pepsin, the polyphenol layer is tannin or tannic acid, and the shell structure is degradable by pepsin.
来源网站:
中国工程科技知识中心
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http://www.ckcest.cn/home/

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