A LED lamp with a LED lamp light guide of ultra-high brightness and large angle, comprises a lamp holder, a lampshade, a LED light source, and the light guide. The lamp holder is fastened with the lampshade, the LED light source is arranged in the lamp holder and connected to a power source through the lamp holder, the light guide is arranged inside the lamp holder and the lampshade, and the light guide is a long bar with four wing plates perpendicularly connected to each other in a cross shape when viewed longitudinally. Four supporting feet are arranged at one end of the light guide and are in clamping connection with the LED light source, and the surface, supported by the four supporting feet, of the light guide is the light incident surface of the light guide; cross grains are arranged on the side surface extending from the other end of the light guide to the middles of the four wing plates, on the edges of two plate surfaces of each wing plate are provided two grooves corresponding to each other, and the
