Alma Mater Studiorum - Universita' Di Bologna;Alma Mater Studiorum - Universita Di Bologna
发明人:
Campadelli, Gabriella,Menotti, Laura
申请号：
AU2008357065
公开号：
AU2008357065B2
申请日:
2008.05.29
申请国别(地区):
AU
年份:
2013
代理人:
摘要：
A modified Herpes Simplex Virus (HSV), which has a portion of gD (glycoprotein D) of the glycoproteic envelope deleted and a heterologous single chain antibody inserted in place of such deleted portion； the modified HSV is capable of infecting cells through receptor HER2/ErbB2 but not through receptors HVEM/HveA and nectinl/HveC； uses of the modified HSV and a process of the preparation thereof are also disclosed.
