There is provided the use of transforming growth factor -β receptor inhibitors for inhibiting SOLVED] ocular scarring. Pharmaceutical compositions useful for the prevention of subconjunctival scarring comprising an effective amount of [SOLUTION] ALK-5 inhibitor, can occur after the GFS. A method of treating a disorder or disease or fibrosis ocular scarring, including other PVR and corneal haze which can be expressed after injury or eye surgery, those so disclosed, medicaments containing the ALK-5 inhibitor and which method comprises applying to the site of trauma or surgery an amount of a composition. [Selection] Figure Figure 1【課題】眼球瘢痕化を抑制するための形質転換成長因子-β受容体阻害剤の使用を提供する。【解決手段】ALK-5阻害剤の有効量を含む、GFS後に生じ得る結膜下瘢痕化の予防に有用な医薬組成物。同様に開示されるものは、眼科手術又は外傷後に発現し得る角膜の濁り及びPVRを含む他の眼球瘢痕化又は線維症の障害又は病気の治療方法であって、ALK-5阻害剤を含む医薬組成物のある量を術後又は外傷部位へ適用することを含む方法である。【選択図】図1
