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Method for reducing scarring during wound healing using antisense compounds directed to CTGF
专利权人:
Nicholas M. Dean;Zol Kryger;Mark Sisco;C. Frank Bennett;Thomas A. Mustoe
发明人:
Thomas A. Mustoe,Nicholas M. Dean,Mark Sisco,Zol Kryger,C. Frank Bennett
申请号:
US12547481
公开号:
US08946172B2
申请日:
2009.08.26
申请国别(地区):
US
年份:
2015
代理人:
摘要:
This invention provides a method for reducing hypertropic scarring resulting from dermal wound healing in a subject in need which comprises administering to the subject an antisense oligonucleotide which inhibits expression of connective tissue growth factor (CTGF) in an amount effective to inhibit expression of CTGF and thereby reduce hypertrophic scarring.
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