Disclosed herein are novel devices comprising small, ultra-low power microelectronic components. In some instances, the microelectronic components is combined with a biosensor component that enablesin situdetection of biomolecules. Also disclosed herein are methods of detecting signal analytes and methods of monitoring the health of a patient using these novel devices.本文揭露的是包含小型超低功率微電子元件的新穎裝置。在一些情況下,該微電子元件與生物感測器元件結合,從而能夠原位檢測生物分子。本文還揭露了使用該等新穎裝置檢測訊號分析物的方法和監測患者健康的方法。