< Topic >This invention has designated that the organism nervous guide who possesses satisfactory organism compatibility is offered as purpose.SolutionsBecause of this, as the organism nervous guide in order to transplant into the human body, step and minimize the antigen of the said membrane origin step and tan the said membrane step and the active layer which it builds a bridge and lock step and the said membrane which offer the natural animal organizational membrane and cylindrical condition on the inside surface of the said membrane step and the said membrane which the coupling are done size of desire and step and the said membrane which are cut off in form the fragment displays, step and the spiral condition backing which arrange the fragment of the said membrane on the mold of rod condition (2) the said fragment of the said membraneIt produces the step which is installed on the outer part surface and, with the method of including.< Selective figure >Figure 1【課題】本発明は、良好な生体適合性を有する生体神経ガイドを提供することを目的としている。【解決手段】このため、人体内に移植するための生体神経ガイドを、天然の動物組織膜を提供するステップと、該膜を架橋かつ固定するステップと、該膜由来の抗原を最小化するステップと、該膜をなめすステップと、活性層を該膜の内表面にカップリングするステップと、該膜を所望の寸法と形状に切断するステップと、該膜の切片が円筒形状を呈するよう、該膜の切片をロッド状の鋳型上に配置するステップと、らせん状支持体(2)を該膜の該切片の外側表面に取り付けるステップと、を含む方法により作製する。【選択図】図1
