California Institute of Technology;Axial Biotherapeutics, Inc.
发明人:
Timothy Sampson,Sarkis Mazmanian,Anthony Stewart Campbell
申请号:
US16611406
公开号:
US20200163933A1
申请日:
2018.05.14
申请国别(地区):
US
年份:
2020
代理人:
摘要:
The present disclosure provides methods and compositions for the prevention, amelioration, or alleviation of one or more neurological disorders associated with microbially-induced amyloid formation. Methods of inhibiting, ameliorating, reducing the likelihood, delaying the onset of, treating, or preventing an amyloid disorder are disclosed. Methods of identifying compounds capable of inhibiting the formation of microbially-induced amyloid fibrils are disclosed.