您的位置: 首页 > 农业专利 > 详情页

TREATMENT OF PATIENTS AFTER STENT IMPLANTATION OR BALLOON DILATATION AND DRUG ELUTING STENTS
专利权人:
发明人:
申请号:
EP10742003.6
公开号:
EP2467480A1
申请日:
2010.08.13
申请国别(地区):
EP
年份:
2012
代理人:
摘要:
The present invention relates to a nucleic acid molecule for use in the treatment or preventive treatment of a patient after stent implantation or balloon dilatation, wherein the nucleic acid molecule is selected from (a) a single-stranded nucleic acid molecule comprising or consisting of the sequence of SEQ ID NO: 1, 2, 3 or 4 or a sequence having at least 90% sequence identity to the sequence of SEQ ID NO: 1, 2, 3 or 4 (b) a hairpin RNA, wherein one of the regions forming the double-stranded portion of said hairpin RNA comprises or consists of the sequence of SEQ ID NO: 1, 2, 3 or 4 or a sequence having at least 90% sequence identity to the sequence of SEQ ID NO: 1, 2, 3 or 4 (c) an at least partially double-stranded RNA comprising two separate single strands, wherein a region within one of the strands, said region being located within the double-stranded portion of said double-stranded RNA, comprises or consists of the sequence of SEQ ID NO: 1, 2, 3 or 4 or a sequence having at least 90% sequence identity to the sequence of SEQ ID NO: 1, 2, 3 or 4 (d) a nucleic acid molecule encoding the nucleic acid molecule of (a) or the RNA (b) and (e) a nucleic acid molecule or a two nucleic acid molecules encoding the two separate single strands of the RNA of (c). The present invention also relates to a drug eluting stent comprising the nucleic acid molecule according to the invention.La présente invention concerne une molécule d’acide nucléique pour utilisation dans le traitement ou le traitement préventif d’un patient après implantation de stent ou dilatation au ballonnet, où la molécule d’acide nucléique est choisie parmi (a) une molécule d’acide nucléique monocaténaire comprenant ou constituée de la séquence de SEQ ID NO: 1, 2, 3 ou 4 ou dune séquence ayant au moins 90 % d’identité de séquence avec la séquence de SEQ ID NO: 1, 2, 3 ou 4 (b) un ARN en épingle à cheveux, où l’une des régions formant la partie bicaténaire dudit ARN en épingle à cheveux comprend ou est cons
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

意 见 箱

匿名:登录

个人用户登录

找回密码

第三方账号登录

忘记密码

个人用户注册

必须为有效邮箱
6~16位数字与字母组合
6~16位数字与字母组合
请输入正确的手机号码

信息补充