The invention features devices for positioning and supporting the limb (e.g., an arm or leg) of a patient. The devices provide adjustable support for, e.g., the upper and lower leg. In addition, the device provides unfettered access to the patients extremities and joints (e.g., the knee and portions of the leg above and below the knee). The invention further features methods of using the devices during diagnostic review, surgery, and rehabilitation. In addition, the invention features methods of treating a patient having a bone or tissue defect by using a device described herein.
