INHIBITEURS D'ARGINASE EN TANT QU'AGENTS THÉRAPEUTIQUES

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专利权人:

Mars; Incorporated

发明人:

申请号：

EP16150285.1

公开号：

EP3034509A1

申请日:

2011.10.19

申请国别(地区):

EP

年份:

2016

代理人:

摘要：

Compounds according to Formula I are potent inhibitors of Arginase I and II activity:where R1, R2, R3, R4, D, W, X, Y, and Z are defined in the specification. The invention also provides pharmaceutical compositions of the compounds and methods of their use in treating or preventing a disease or a condition associated with arginase activity.

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