VAN ZANDT, MICHAEL,GOLEBIOWSKI, ADAM,JI, MIN, KOO,WHITEHOUSE, DARREN,RYDER, TODD,BECKETT, PAUL
申请号:
SG2012077970
公开号:
SG184956A1
申请日:
2011.04.20
申请国别(地区):
SG
年份:
2012
代理人:
摘要:
Compounds according to Formula I and Formula II are potent inhibitors of Arginase I and II activity : Formule (I), (II) where R1, R2, R3, R4, R5, R6, R7, R8, R9, D, M, X, and Y are defined as set forth in the specification. The invention also provides pharmaceutical compositions of the compounds and methods of their use for treating or preventing a disease or a condition associated with arginase activity.