Adam Golebiowski;Paul Beckett;Todd Ryder;Darren Whitehouse;Min Koo Ji;Michael Van Zandt
发明人:
Michael Van Zandt,Adam Golebiowski,Min Koo Ji,Darren Whitehouse,Todd Ryder,Paul Beckett
申请号:
US13090714
公开号:
US20120083469A1
申请日:
2011.04.20
申请国别(地区):
US
年份:
2012
代理人:
摘要:
Compounds according to Formula I and Formula II are potent inhibitors of Arginase I and II activity:where R1, R2, R3, R4, R5, R6, R7, R8, R9, D, M, X, and Y are defined as set forth in the specification. The invention also provides pharmaceutical compositions of the compounds and methods of their use for treating or preventing a disease or a condition associated with arginase activity.