Crich, Joyce Z.,Henry, James Robert,Slater, Melissa Kate,Brooks, Harold Burns,Wang, Yan,Li, Hong-Yu
申请号：
AU2007334039
公开号：
AU2007334039B2
申请日:
2007.12.11
申请国别(地区):
AU
年份:
2012
代理人:
摘要：
The present invention provides novel imidazolidinonyl aminopyrimidine compoundsbelieved to have clinical use for treatment of cancer through inhibiting Plk1.wherein: R hydrogen, hydroxy, halo, methyl, C-Calkoxy, amino, or rnethylamino； R is hydrogen, halo, or cyano； Ris hydrogen or halo；, R is hydrogen, halo, or methyl； provided thatat least two of R, R, R, and R arehydrogen； R is hydrogen, halo, or methyl； or a pharmaceutically acceptablesalt thereof.
