WAGENINGEN UNIVERSITEIT;UNIVERSITE CATHOLIQUE DE LOUVAIN
发明人:
Clara BELZER,Willem Meindert DE VOS,Patrice Daniel CANI
申请号：
US15571175
公开号：
US20180265554A1
申请日:
2016.05.04
申请国别(地区):
US
年份:
2018
代理人:
摘要：
It has been found that an extracellular polypeptide derived from Akkermansia municiphila is capable of modulating and/or promoting gut mucosal immune system function and/or maintaining and/or restoring metabolic status and/or increasing the physical integrity of the gut mucosal barrier in a mammal. The polypeptide or host cells including such polypeptide may be employed to prevent and/or treat a variety of conditions that benefit from an increased physical integrity of the gut mucosal barrier and/or an improved gut mucosal immune system function and metabolic status.
