A similarity-computation apparatus, a side effect determining apparatus and a system for calculating similarities between drugs and using the similarities
Emir Fernando Munoz Jiménez,Ahmed Abdelrahman,Vit Novacek,Pierre-Yves Vandenbussche
申请号:
GB20150007501
公开号:
GB2537925(A)
申请日:
2015.04.30
申请国别(地区):
英国
年份:
2016
代理人:
摘要:
A system for calculating similarities between drugs and using the similarities to extrapolate side effects of a specified drug comprising: a similarity-computation apparatus configured to use open data to compute similarities between drugs, with: a data integration module configured to obtain data related to a set of drugs from a plurality of open data sources and to integrate the data to generate RDF triples; an RDF module configured to store an RDF graph of the RDF triples; and a similarity calculation module configured to retrieve a list of all the drugs present in the RDF graph and to calculate the similarity of each drug with every other drug in the RDF graph, for storage in a similarity database; and a side effect determining apparatus configured to extrapolate side effects of a specified drug from open data related to the set of drugs, with: a connection to the similarity database; a user interface configured to allow a user to specify a drug from the set of drugs; a neighbours ranking module configure