1. A composition comprising apixaban crystalline particles having an average particle size equal to or less than about 89 microns and a pharmaceutically acceptable diluent or nositel.2. A composition according to claim 1, wherein said composition comprises Form N-1 apiksabana.3. A composition according to claim 1, wherein the particles have a D, equal to or less than 89 mkm.4. A composition according to any one of claims 1-3, wherein the particles have a D, equal to or less than 50 mkm.5. A composition as claimed in any one of claims 1-3, wherein the particles have a D, equal to or less than 30 mkm.6. A composition according to any one of claims 1-3, wherein the particles have a D, equal to or less than 25 mkm.7. A composition according to claim 1, which demonstrates AUC and / or C, which are at least 80% of the mean AUC and / or C, observed for an equivalent composition differing only in that the average value of apixaban particle size is 89 mkm.8. A composition according to claim 1, which demonstrates AUC and / or C, which are at least 80% of the mean AUC and / or C, observed for an equivalent composition differing only in that the average value of apixaban particle size is 85 mkm.9. A composition according to any one of claims 1-3, 7, 8, further comprising from 1% to 2% by weight of surfactant veschestva.10. A composition according to claim 9, wherein the surfactant is sodium lauryl natriya.11. A composition according to any one of claims 1-3, 7, 8, 10 for use in treating thromboembolic oslozhneniya.12. A composition comprising apixaban crystalline particles having an average particle size equal to or less than about 85 microns and a pharmaceutically acceptable diluent or nositel.13. A composition according to claim 12, wherein said composition comprises Form N-1 apixaban1. Композиция, содержащая кристаллические частицы апиксабана, имеющие средний размер частиц, равный или меньший, чем около 89 мкм и фармацевтически приемлемый разбавитель или носитель.2. Композиц
