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Solid dispersion comprising 20-O-ß-D-glucopyranosyl-20S-protopanaxadiol
专利权人:
发明人:
이성균,박용덕,장재원,허봉행,지상철
申请号:
KR1020090121077
公开号:
KR1011833840000B1
申请日:
2009.12.08
申请国别(地区):
KR
年份:
2012
代理人:
摘要:
PURPOSE: A solid dispersion containing 20-O-beta-D-glucopyranosyl-20(S)-protopanaxadiol and saturated polyglycolated glyceride is provided. CONSTITUTION: A solid dispersion contains 20-O-beta-D-glucopyranosyl-20(S)-protopanaxadio as a pharmacologically active ingredient and saturated polyglycosylated glyceride as a lipid matrix. The saturated polyglycolated glyceride is a mixture of mono-, di- and tri-glyceride and polyethylene glyceride and mono- and di-ester of polyethylene glycol. The solid dispersion is a capsule. A pharmaceutical formulation contains the solid dispersion and pharmaceutically acceptable additive. The formulation is a capsule or table.본 발명은 약리학적 활성성분인 20-O-β-D-글루코피라노실-20(S)-프로토파낙사디올 및 지질 매트릭스인 포화 폴리글리콜화 글리세라이드를 포함하는 고체분산체를 제공하며, 본 발명의 고체분산체는 20-O-β-D-글루코피라노실-20(S)-프로토파낙사디올의 용출률을 증가시키는 작용효과를 갖는다.
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中国工程科技知识中心
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