Waleed Danho,David Charles Fry,Robert Alan Goodnow, Jr.,Wajiha Khan,Joseph Swistok,Jefferson Wright Tilley
申请号:
US12547076
公开号:
US08299023B2
申请日:
2009.08.25
申请国别(地区):
US
年份:
2012
代理人:
摘要:
Provided herein are neuropeptide-2 receptor agonists of the formula (I):Y—R1—R2—X—R3—R4—R5—R6—R7—R8—R9—R10—R11—R12—R13—R14—NH2 (I) (SEQ ID NO: 1),as well as pharmaceutically acceptable salts, derivatives and fragments thereof, wherein the substituents are as those disclosed in the specification. These compounds, and the pharmaceutical compositions containing them, are useful for the treatment of diseases such as, for example, obesity and diabetes.