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Neuropeptide-2 receptor (Y-2R) agonists and uses thereof
专利权人:
Karin Conde-Knape
发明人:
Karin Conde-Knape,Waleed Danho,George Ehrlich,Nader Fotouhi,David Charles Fry,Wajiha Khan,Anish Konkar,Cristina Martha Rondinone,Joseph Swistok,Rebecca Anne Taub,Jefferson Wright Tilley
申请号:
US12536688
公开号:
US08268784B2
申请日:
2009.08.06
申请国别(地区):
US
年份:
2012
代理人:
摘要:
Provided herein are neuropeptide-2 receptor agonists of the formula (I):as well as pharmaceutically acceptable salts, derivatives and fragments thereof, wherein the substituents are as those disclosed in the specification. X is 4-oxo-6-(1-piperazinyl)-3(4H)-quinazoline-acetic acid (Pqa). These compounds, and the pharmaceutical compositions containing them, are useful for the treatment of diseases such as, for example, obesity and diabetes.
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