6-HETEROCYCLYL-4-MORPHOLIN-4-YLPYRIDINE-2-ONE COMPOUNDS农业专利-农业学术服务平台

发明人:: MARTINSSON, JESSICA,马丁松杰西卡,馬丁松傑西卡,ANDERSSON, MARTIN,安德森马丁,安德森馬丁,LINDSTROM, JOHAN,林斯特龙约翰,林斯特龍約翰,FORSBLOM, RICKARD,佛斯伯龙理查,佛斯伯龍理查,RAHM, FREDRIK,拉姆弗雷德里克,拉姆弗雷德里克,GINMAN, TOBIAS,金曼托比亚斯,金曼托比亞斯,VI

摘要：: The invention provides novel6-heterocyclyl-4-morpholin-4-yl-pyridine-2-one compoundsof formula (I), pharmaceutical compositions containing such compounds, and methods for using such compounds in treatment of diseases including cancer, diabetes,inflammatory disease, neurodegenerative disorders, cardiovascular disorders and viral infections;wherein R1, R2, R3and A are as defined in the specification.本發明提供一種新穎的,具有式(I)結構的6-雜環基-4-嗎啉-4-芳基 - 吡啶-2-酮化合物,含有這些化合物的藥理組成物,以及這些化合物於治療疾病中的應用方法,這些疾病包括癌症,糖尿病,發炎性疾病,神經退化性疾病,心血管疾病疾病和病毒感染;其中R1, R2, R3及 A如說明書中所定義。