用於治療發炎性病症及骨關節炎之新穎化合物及其醫藥組合物农业专利-农业专业知识服务系统

发明人:: LABEGUERE, FREDERIC GILBERT,拉贝吉叶赫　菲迪克　吉尔柏,拉貝吉葉赫　菲迪克　吉爾柏,HENG, RAMA,衡　拉玛,衡　拉瑪,DE CEUNINCK, FREDERIC ANDRE,瑟尼克　费德克　安德烈,瑟尼克　費德克　安德烈,ALVEY, LUKE JONATHAN,艾尔维　路克　乔纳森,艾爾維　路克　喬納森,AMANTINI, DAVID,阿曼提尼　大卫,阿曼提尼,拉贝吉叶赫菲迪克吉尔柏,拉貝吉葉赫菲迪克吉爾柏,衡拉玛,衡拉瑪,瑟尼克费德克安德烈,瑟尼克費德克安德烈,艾尔维路克乔纳森,艾爾維路克喬納森,阿曼提尼大卫

摘要：: The present invention discloses a compound according to Formula I:The present invention relates to a compound inhibiting ADAMTS, methods for its production, pharmaceutical compositions comprising the same, and methods of treatment using the same, for the prophylaxis and/or treatment of inflammatory diseases, and/or diseases involving degradation of cartilage and/or disruption of cartilage homeostasis by administering the compound of the invention.本發明揭示一種式I化合物，。本發明係關於抑制ADAMTS之化合物、其產生方法、包含其之醫藥組合物及使用其之治療方法，該等方法係藉由投與本發明之化合物用於預防及/或治療發炎性疾病及/或涉及軟骨退化及/或軟骨恆定破壞之疾病。