Rajpal, Arvind,Potluri, Shobha Chowdary,Poirot, Laurent,Juillerat, Alexandre,Pertel, Thomas Charles,Stone, Donna Marie,Sasu, Barbra Johnson
申请号：
AU2015344769
公开号：
AU2015344769A1
申请日:
2015.11.09
申请国别(地区):
AU
年份:
2017
代理人:
摘要：
The invention relates to an inhibitory chimeric antigen receptor (N-CAR) comprising an extracellular domain comprising an antigen binding domain, a transmembrane domain, and, an intracellular domain wherein the intracellular domain comprises an Immunoreceptor Tyrosine-based Switch Motif ITSM, wherein said ITSM is a sequence of amino acid TX
