JONES, FRANK R.,BALINT, JOSEPH,RICE, ADRIAN,LATCHMAN, YVETTE,GABITZSCH, ELIZABETH
申请号:
CA3030447
公开号:
CA3030447A1
申请日:
2017.07.14
申请国别(地区):
CA
年份:
2018
代理人:
摘要:
Compositions of a recombinant adenovirus based vector vaccine containing one or more flavivirus antigen genes are disclosed herein. Methods for constructing and producing such vaccines and methods of using these vaccines to generate immune responses against flaviviruses are also described. Compositions described herein allow for vaccinations in subjects with preexisting immunity to adenovirus.