Frank R. JONES,Joseph BALINT,Adrian RICE,Yvette LATCHMAN,Elizabeth GABITZSCH
申请号：
US16317747
公开号：
US20200172925A1
申请日:
2017.07.14
申请国别(地区):
US
年份:
2020
代理人:
摘要：
Compositions of a recombinant adenovirus based vector vaccine containing one or more alphavirus antigen genes are disclosed herein. Methods for constructing and producing such vaccines and methods of using these vaccines to generate broad based immune responses against alphaviruses are also described. Compositions described herein allow for vaccinations in individuals with preexisting immunity to adenovirus.
