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Simulation of bifurcated lens group by tubricin
专利权人:
ХАНЧЖОУ ДАК БАЙОТЕК КО. ЛТД
发明人:
Чжао, Роберт Юнсинь,Ян, Цинлян,Хуан, Юаньюань,Чжао, Линьяо,Гай, Шунь,Е, Ханбо,Лэй, Цзюнь,Сюй, Ифан,Цао, Минцзюнь,Го, Хуэйхуэй,Цзя, Цзюньсян,Тун, Цяньцянь,Ли, Вэньцзюнь,Чжоу, Сяомай,Се, Хуншэн,Бай, Лу
申请号:
EA202091217
公开号:
EA202091217A1
申请日:
2017.12.31
申请国别(地区):
EA
年份:
2020
代理人:
摘要:
The present invention relates to the conjugation of a tubulysin analog compound to a cell-binding molecule with branched/side-chain linkers for having better delivery of the conjugate compound and targeted treatment of abnormal cells. It also relates to a branched-linkage method of conjugation of a tubulysin analog molecule to a cell-binding ligand, as well as methods of using the conjugate in targeted treatment of cancer, infection and autoimmune disease.
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