The present invention relates to compound relevant intimate contact between prevention is by sexual intercourse or companion and obtain purposes in the medication preparation that HIV infects, wherein this compound is formula (I) compound, its N-oxide compound, pharmaceutically acceptable addition salt, quaternary amine and stereochemistry heterogeneous forms thereof Wherein comprise-a 1=a 2-a 3=a 4-and-b 1=b 2-b 3=b 4-ring represent phenyl, pyridyl, pyrimidyl, pyrazinyl, pyridazinyl Also relate to the medicinal compositions that comprises described compound.