ETO, KOJI,NAKAUCHI, HIROMITSU,TAKAYAMA, NAOYA,NAKAMURA, SOU
申请号:
EP12785650
公开号:
EP2708597A4
申请日:
2012.05.11
申请国别(地区):
EP
年份:
2014
代理人:
摘要:
An object of the present invention is to provide a method of promoting polyploidization of megakaryocytes and thereby producing highly polyploidized megakaryocytes, a method of efficiently producing platelets from polyploidized megakaryocytes, and the like. The present invention provides a method of producing polyploidized megakaryocytes comprising a step of forcing expression of an apoptosis suppressor gene in megakaryocytes before polyploidization and culturing the resulting cells.