ETO, KOJI,NAKAUCHI, HIROMITSU,TAKAYAMA, NAOYA,NAKAMURA, SOU
申请号:
CA2836073
公开号:
CA2836073A1
申请日:
2012.05.11
申请国别(地区):
CA
年份:
2012
代理人:
摘要:
An object of the present invention is to provide amethod of promoting polyploidization of megakaryocytes andthereby producing highly polyploidized megakaryocytes, amethod of efficiently producing platelets frompolyploidized megakaryocytes, and the like. The presentinvention provides a method of producing polyploidizedmegakaryocytes comprising a step of forcing expression ofan apoptosis suppressor gene in megakaryocytes beforepolyploidization and culturing the resulting cells.