Koji Eto,Hiromitsu Nakauchi,Naoya Takayama,Sou Nakamura
申请号：
US15680920
公开号：
US10533185B2
申请日:
2017.08.18
申请国别(地区):
US
年份:
2020
代理人:
摘要：
An object of the present invention is to provide a method of promoting polyploidization of megakaryocytes and thereby producing highly polyploidized megakaryocytes, a method of efficiently producing platelets from polyploidized megakaryocytes, and the like. The present invention provides a method of producing polyploidized megakaryocytes comprising a step of forcing expression of an apoptosis suppressor gene in megakaryocytes before polyploidization and culturing the resulting cells.
