PROCÉDÉ DE SYNTHÈSE DE 2-HYDROXY-6-((2- (1-ISOPROPYL-1H-PYRAZOL-5-YL)PYRIDIN-3-YL)MÉTHOXY)BENZALDÉHYDE

• 收藏
• 分享

专利权人:

Global Blood Therapeutics; Inc.

发明人:

LI, Zhe,GUZ, Nathan,SHAO, Yiyang,COCUZ, Julieana,FRIESER, Markus,YIANNIKOUROS, George, Petros,LIAO, Liang

申请号：

EP17796828

公开号：

EP3454854A4

申请日:

2017.05.11

申请国别(地区):

EP

年份:

2019

代理人:

摘要：

Disclosed herein are processes for synthesizing 2-hydroxy-6-((2-(1-isopropyl-1H-pyrazol-5-yl)-pyridin-3-yl)methoxy)benzaldehyde (also referred to herein as Compound (I)) and intermediates used in such processes. Compound (I) binds to hemoglobin and increases it oxygen affinity and hence can be useful for the treatment of diseases such as sickle cell disease.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/