PROCESS FOR SYNTHESIZING 2-HYDROXY-6-((2-(1-ISOPROPYL-1H-PYRAZOL-5-YL)-PYRIDIN-3-YL)METHOXY)BENZALDEHYDE

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专利权人:

INC.;GLOBAL BLOOD THERAPEUTICS

发明人:

LI, Zhe,GUZ, Nathan,SHAO, Yiyang,COCUZ, Julieana,FRIESER, Markus,YIANNIKOUROS, George,LIAO, Liang

申请号：

SG11201809344Q

公开号：

SG11201809344QA

申请日:

2017.05.11

申请国别(地区):

SG

年份:

2018

代理人:

摘要：

Disclosed herein are processes for synthesizing 2-hydroxy-6-((2-(1-isopropyl-1H-pyrazol-5-yl)-pyridin-3-yl)methoxy)benzaldehyde (also referred to herein as Compound (I)) and intermediates used in such processes. Compound (I) binds to hemoglobin and increases it oxygen affinity and hence can be useful for the treatment of diseases such as sickle cell disease.

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中国工程科技知识中心

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